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JoVE Journal
Developmental Biology

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Three-dimensional Organotypic Cultures of Vestibular and Auditory Sensory Organs
 

Three-dimensional Organotypic Cultures of Vestibular and Auditory Sensory Organs

Article doi: 10.3791/57527
June 1st, 2018

Summary June 1st, 2018

Three-dimensional organotypic cultures of the murine utricle and cochlea in optically clear collagen I gels preserve innate tissue morphology, allow for mechanical stimulation through adjustment of matrix stiffness, and permit virus-mediated gene delivery.

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