A subscription to JoVE is required to view this content. Sign in or start your free trial.
Chapters
- 00:04Title
- 00:59Standard Protocol for the Separation of Aromatic Aldehydes from a Mixture
- 02:16Separation of Aliphatic Aldehydes and Ketones from a Mixture
- 04:00Separation of Aldehydes from a Mixture Containing an Alkene
- 05:00Re-isolation of Aldehydes from a Mixture
- 07:01Results: Representative 1H NMR Indicates Success of Separation
- 08:21Conclusion
Here, we present a protocol to remove aldehydes and reactive ketones from mixtures by a liquid-liquid extraction protocol directly with saturated sodium bisulfite in a miscible solvent. This combined protocol is rapid and facile to perform. The aldehyde or ketone can be re-isolated by the basification of the aqueous layer.
