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Veno-Venous Extracorporeal Membrane Oxygenation in a Mouse

Article DOI: 10.3791/58146-v • 06:41 min • October 24th, 2018
October 24th, 2018 •
1, 1, 1, 1, 1, 1, 1, 1, *2, *1
1Department of Cardiothoracic, Transplantation, and Vascular Surgery, Hannover Medical School, 2Department of Pneumology, Hannover Medical School
* These authors contributed equally

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Summary
Automatic Translation

Here we present a protocol describing the technique of veno-venous extracorporeal membrane oxygenation (ECMO) in a non-intubated, spontaneously breathing mouse. This murine model of ECMO can be effectively implemented in experimental studies of acute and end-stage lung diseases.

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Veno-Venous Extracorporeal Membrane Oxygenation Pulmonary Research Acute Lung Disease Chronic Lung Disease Multi-organ Damage Extracorporeal Membrane Oxygenation Life-saving Procedure Surgical Blade Dissecting Microscope Polyurethane Catheter Fenestrations Outflow Cannula Priming Solution Peristaltic Pump Oxygenator Toe Pinch Response Anesthetized Mouse Ointment Lateral Skin Incision Jugular Vein Micro-forceps Cotton Swabs Silk Suture Heparin Injection
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