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Syntese av 68Ga Core-dopet jernoksid nanopartikler dobbelt fantes et Positron utslipp stengte / (T1) magnetisk resonans Imaging
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Syntese av 68Ga Core-dopet jernoksid nanopartikler dobbelt fantes et Positron utslipp stengte / (T1) magnetisk resonans Imaging

Article DOI: 10.3791/58269-v • 07:26 min • November 20th, 2018
November 20th, 2018 •
1, 2, 1, 3
1Nanobiotechnology, Molecular Imaging and Metabolomics Lab, Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC), 2CIC biomaGUNE and CIBER de Enfermedades Respiratorias (CIBERES). Ikerbasque, Basque Foundation for Science, Universidad Complutense de Madrid (UCM), 3Advanced Imaging Unit, Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC), CIBER de Enfermedades Respiratorias (CIBERES)

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Her presenterer vi en protokoll for å få68Ga core-dopet jernoksid nanopartikler via fast mikrobølgeovn-drevet syntese. Metodikken gjengir PET / (T1) MRI nanopartikler med radiolabeling effektivitet høyere enn 90% og radiochemical renhet 99% i en 20 minutters syntese.

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Biologi problemet 141 jernoksid nanopartikler 68Ga fantes et positron utslipp tomografi magnetisk resonans imaging mikrobølgeovn syntese sitronsyre
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