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Syntesen av 68Ga Core-dopade järnoxid nanopartiklar för dubbla positronemissionstomografi / (T1) Magnetic Resonance Imaging
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Syntesen av 68Ga Core-dopade järnoxid nanopartiklar för dubbla positronemissionstomografi / (T1) Magnetic Resonance Imaging

Article DOI: 10.3791/58269-v • 07:26 min • November 20th, 2018
November 20th, 2018 •
1, 2, 1, 3
1Nanobiotechnology, Molecular Imaging and Metabolomics Lab, Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC), 2CIC biomaGUNE and CIBER de Enfermedades Respiratorias (CIBERES). Ikerbasque, Basque Foundation for Science, Universidad Complutense de Madrid (UCM), 3Advanced Imaging Unit, Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC), CIBER de Enfermedades Respiratorias (CIBERES)

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Här presenterar vi ett protokoll att erhålla68Ga core-dopade järnoxid nanopartiklar via snabbt mikrovågsugn-driven syntes. Metoden gör PET / (T1) MRI nanopartiklar med radiolabeling effektivitet högre än 90% och radiokemisk renhet av 99% i en 20-minuters syntes.

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Biologi fråga 141 järnoxid nanopartiklar 68Ga positronemissionstomografi magnetisk resonanstomografi mikrovågsugn syntes citronsyra
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