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Evaluating the Anti-depression Effect of Xiaoyaosan on Chronically-stressed Mice
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JoVE Journal Behavior
Evaluating the Anti-depression Effect of Xiaoyaosan on Chronically-stressed Mice

Evaluating the Anti-depression Effect of Xiaoyaosan on Chronically-stressed Mice

DOI:
10.3791/58276-v

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06:08 min

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January 07, 2019

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, , , ,
1School of Traditional Chinese Medicine,Beijing University of Chinese Medicine, 2Formula-pattern Research Center, School of Traditional Chinese Medicine,Jinan University

Chapters

  • 00:04Title
  • 01:13Induction of Depression in Mice
  • 02:41Sucrose Preference Test
  • 03:29Open Field Test
  • 04:16Results: Model Mice Behavior Improved by the Treatment of Xiaoyaosan and Fluoxetine
  • 05:09Conclusion

Summary

Automatic Translation

Automatic Translation

Here, we present a protocol to establish the mouse depressive model, observe the behavior changes associated with chronic unpredictable mild stress (CUMS), and evaluate the anti-depression effect of Xiaoyaosan.

Tags

Keywords: DepressionAnti-depressionXiaoyaosanTraditional Chinese MedicineChronic StressMice ModelSucrose Preference TestCoat StateBody WeightPre-clinic ResearchStandardized Protocol

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