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JoVE Journal
Immunology and Infection

This content is Open Access.

Immunization of Adult Zebrafish for the Preclinical Screening of DNA-based Vaccines
 

Immunization of Adult Zebrafish for the Preclinical Screening of DNA-based Vaccines

Article DOI: 10.3791/58453
October 30th, 2018

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Summary October 30th, 2018

Here we describe a protocol for the immunization of the adult zebrafish (Danio rerio) with a DNA-based vaccine and demonstrate the validation of a successful vaccination event. This method is suitable for the preclinical screening of vaccine candidates in various infection models.

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