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Chemistry

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Methionine Functionalized Biocompatible Block Copolymers for Targeted Plasmid DNA Delivery
 

Methionine Functionalized Biocompatible Block Copolymers for Targeted Plasmid DNA Delivery

Article doi: 10.3791/58527
August 6th, 2019

Summary August 6th, 2019

This work presents the preparation of methionine functionalized biocompatible block copolymers (mBG) via the reversible addition-fragmentation chain transfer (RAFT) method. The plasmid DNA complexing ability of the obtained mBG and their transfection efficiency were also investigated. The RAFT method is very beneficial for polymerizing monomers containing special functional groups.

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