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JoVE Journal
Genetics

This content is Open Access.

CRISPR-mediated Genome Editing of the Human Fungal Pathogen Candida albicans
 

CRISPR-mediated Genome Editing of the Human Fungal Pathogen Candida albicans

Article doi: 10.3791/58764
November 14th, 2018

Summary November 14th, 2018

Efficient genome engineering of Candida albicans is critical to understanding the pathogenesis and development of therapeutics. Here, we described a protocol to quickly and accurately edit the C. albicans genome using CRISPR. The protocol allows investigators to introduce a wide variety of genetic modifications including point mutations, insertions, and deletions.

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