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JoVE Journal
Biochemistry

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Identification of Functional Protein Regions Through Chimeric Protein Construction
 

Identification of Functional Protein Regions Through Chimeric Protein Construction

Article DOI: 10.3791/58786-v
January 8th, 2019

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Summary January 8th, 2019

Structurally related proteins frequently exert distinct biological functions. The exchange of equivalent regions of these proteins in order to create chimeric proteins constitutes an innovative approach to identify critical protein regions that are responsible for their functional divergence.

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