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JoVE Journal
Immunology and Infection

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Induction of Intestinal Graft-versus-host Disease and Its Mini-endoscopic Assessment in Live Mice
 

Induction of Intestinal Graft-versus-host Disease and Its Mini-endoscopic Assessment in Live Mice

Article doi: 10.3791/58871
February 11th, 2019

Summary February 11th, 2019

Here, we present a protocol that describes allogeneic hematopoietic stem cell transplantation and allows repetitive mini-endoscopic evaluations of the distal colon in situ for the presence, characteristics, and severity of colonic inflammation within live mice suffering from intestinal graft-versus-host disease.

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