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Cancer Research
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Yeast As a Chassis for Developing Functional Assays to Study Human P53
 

Yeast As a Chassis for Developing Functional Assays to Study Human P53

Article doi: 10.3791/59071
August 4th, 2019

Summary August 4th, 2019

Presented here are four protocols to construct and exploit yeast Saccharomyces cerevisiae reporter strains to study human P53 transactivation potential, impacts of its various cancer-associated mutations, co-expressed interacting proteins, and the effects of specific small molecules.

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