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Cancer Research
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Yeast As a Chassis for Developing Functional Assays to Study Human P53
 

Yeast As a Chassis for Developing Functional Assays to Study Human P53

Article DOI: 10.3791/59071-v
August 4th, 2019

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Summary August 4th, 2019

Presented here are four protocols to construct and exploit yeast Saccharomyces cerevisiae reporter strains to study human P53 transactivation potential, impacts of its various cancer-associated mutations, co-expressed interacting proteins, and the effects of specific small molecules.

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