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Journal / Immunology and Infection / En roman menneskelige epitelial Enteroid Model af …
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Immunology and Infection

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JoVE Journal Immunology and Infection
En roman menneskelige epitelial Enteroid Model af nekrotiserende Enterocolitis
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En roman menneskelige epitelial Enteroid Model af nekrotiserende Enterocolitis

Article DOI: 10.3791/59194-v • 08:42 min • April 10th, 2019
April 10th, 2019 •
1, 1, 1, 1, 1,2
1Department of Pediatrics, Northwestern University, 2Division of Pediatric Surgery, Ann & Robert H. Lurie Children's Hospital of Chicago

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Enteroids dukker op som en roman model i studiet af menneskers sygdom. Protokollen beskriver hvordan man simulere en enteroid model af menneskelige nekrotiserende enterocolitis ved hjælp af LPS (LPS) behandling af enteroids genereret fra neonatal væv. Indsamlede enteroids vise inflammatoriske forandringer beslægtet med dem, der ses i menneskelige nekrotiserende enterocolitis.

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Immunologi og infektion spørgsmålet 146 Enteroid epithelial organoid nekrotiserende Enterocolitis LP'ER model intestinal krypt stamceller humane væv model
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