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Journal / Neuroscience / Convection Enhanced Delivery of Optogenetic…
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Neuroscience

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JoVE Journal Neuroscience
Convection Enhanced Delivery of Optogenetic Adeno-associated Viral Vector to the Cortex of Rhesus Macaque Under Guidance of Online MRI Images Convection Enhanced Delivery of Optogenetic Adeno-associated Viral Vector to the Cortex of Rhesus Macaque Under Guidance of Online MRI Images Convection Enhanced Delivery of Optogenetic Adeno-associated Viral Vector to the Cortex of Rhesus Macaque Under Guidance of Online MRI Images Conve
High-resolution Volume Imaging of Neurons by the Use of Fluorescence eXclusion Method and Dedicated Microfluidic Devices
Journal (Neuroscience)
High-resolution Volume Imaging of Neurons by the Use of Fluorescence eXclusion Method and Dedicated Microfluidic Devices
Combining Behavioral Endocrinology and Experimental Economics: Testosterone and Social Decision Making
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Convection Enhanced Delivery of Optogenetic Adeno-associated Viral Vector to the Cortex of Rhesus Macaque Under Guidance of Online MRI Images Convection Enhanced Delivery of Optogenetic Adeno-associated Viral Vector to the Cortex of Rhesus Macaque Under Guidance of Online MRI Images Convection Enhanced Delivery of Optogenetic Adeno-associated Viral Vector to the Cortex of Rhesus Macaque Under Guidance of Online MRI Images Conve

Article DOI: 10.3791/59232-v • 08:52 min • May 23rd, 2019
May 23rd, 2019 •
1,2, 2,3, 4, 1,2,3,4
1Departments of Bioengineering, University of Washington, 2Washington National Primate Research Center, 3Department of Electrical and Computer Engineering, University of Washington, 4Department of Physiology and Center for Integrative Neuroscience, University of California, San Francisco

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Ici, nous démontrons la résonance magnétique (MR)-guidée convection a augmenté la livraison (CED) des vecteurs viraux dans le cortex comme approche efficace et simplifiée pour réaliser l'expression optogénétique à travers de grandes zones corticales dans le cerveau macaque.

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Neurosciences Numéro 147 Optogénétique Primates non humains Macaques rhésus Livraison de vecteurs viraux expression opsine cortex moteur primaire cortex somatosensoriel primaire
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