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JoVE Journal
Cancer Research

This content is Open Access.

Predicting In Vivo Payloads Delivery using a Blood-brain Tumor-barrier in a Dish
 

Predicting In Vivo Payloads Delivery using a Blood-brain Tumor-barrier in a Dish

Article doi: 10.3791/59384
April 16th, 2019

Summary April 16th, 2019

Drug targeting to central nervous system tumors is a major challenge. Here we describe a protocol to produce an in vitro mimic of the blood-brain tumor-barrier using murine and/or human cells and discuss their relevance for the predictability of central nervous system tumor targeting in vivo.

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