A subscription to JoVE is required to view this content. Sign in or start your free trial.
Chapters
- 00:04Title
- 00:46Synthesis of Cyclic (alkyl)(amino) Carbene (Compound 1)
- 05:38Synthesis of the CAAC-NHC Salt (Compound 3prot)
- 07:35Synthesis of the Organic Radical CAAC-NHC-2 (Compound 4)
- 08:44Results: 13C and 1H NMR Spectrum
- 10:10Conclusion
We present protocols for the isolation of stable heterocyclic carbenes. The synthesis of a cyclic (alkyl)(amino) carbene (CAAC) and an N-heterocyclic carbene (NHC) is demonstrated using filter cannulas and Schlenk technique. We furthermore present the synthesis of the related oxygen-sensitive, electron-rich mixed “Wanzlick dimer” and the reduced stable organic radical.
