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JoVE Journal
Genetics

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Exploring Sequence Space to Identify Binding Sites for Regulatory RNA-Binding Proteins
 

Exploring Sequence Space to Identify Binding Sites for Regulatory RNA-Binding Proteins

Article DOI: 10.3791/59635
August 9th, 2019

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Summary August 9th, 2019

Sequence specificity is critical for gene regulation. Regulatory proteins that recognize specific sequences are important for gene regulation. Defining functional binding sites for such proteins is a challenging biological problem. An iterative approach for identification of a binding site for an RNA-binding protein is described here and is applicable to all RNA-binding proteins.

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