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Human Neural Organoids for Studying Brain Cancer and Neurodegenerative Diseases
This content is Free Access.
1Laboratory of Tumor Immunology, Translational Research Center in Onco-Hematology, Department of Internal Medicine Specialties, Faculty of Medicine,University of Geneva, 2Department of Pathology and Immunology, University Medical Center,University of Geneva, 3Laboratory of Toxicology and Therapeutic Drug Monitoring,Geneva University Hospitals, 4Tissue Engineering Laboratory, Hepia/HES-SO,University of Applied Sciences Western Switzerland, 5Laboratory of Experimental cell therapy, Department of Diagnostics,Geneva University Hospitals
Chapters
- 00:04Title
- 00:52hESC-derived Neural Organoids for Glioblastoma Multiforme Studies
- 04:39hESC-derived Dopaminergic Organoids for Parkinson s Disease Studies
- 08:12Results: Generation of Dopaminergic Neural Organoid and Electrophysiological and Morphological Analysis
- 09:14Conclusion
This study introduces and describes protocols to derive two specific human neural organoids as a relevant and accurate model for studying 1) human glioblastoma development within human neural organoids exclusively in humans and 2) neuron dopaminergic differentiation generating a three-dimensional organoid.
