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Studying Left Ventricular Reverse Remodeling by Aortic Debanding in Rodents
 

Studying Left Ventricular Reverse Remodeling by Aortic Debanding in Rodents

Article doi: 10.3791/60036
July 14th, 2021

Summary July 14th, 2021

Here we describe a step-by-step protocol of surgical aorta debanding in the well-established mice model of aortic-constriction. This procedure not only allows studying the mechanisms underlying the left ventricular reverse remodeling and regression of hypertrophy but also to test novel therapeutic options that might accelerate myocardial recovery.

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