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A High-Throughput In Situ Method for Estimation of Hepatocyte Nuclear Ploidy in Mice
 

A High-Throughput In Situ Method for Estimation of Hepatocyte Nuclear Ploidy in Mice

Article doi: 10.3791/60095
April 19th, 2020

Summary April 19th, 2020

We present a robust, cost-effective, and flexible method for measuring changes in hepatocyte number and nuclear ploidy within fixed/cryopreserved tissue samples that does not require flow cytometry. Our approach provides a powerful sample-wide signature of liver cytology ideal for tracking the progression of liver injury and disease.

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