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Hemogenic Reprogramming of Human Fibroblasts by Enforced Expression of Transcription Factors
JoVE Journal
Developmental Biology
This content is Free Access.
JoVE Journal Developmental Biology
Hemogenic Reprogramming of Human Fibroblasts by Enforced Expression of Transcription Factors

Hemogenic Reprogramming of Human Fibroblasts by Enforced Expression of Transcription Factors

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11:42 min

November 04, 2019

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11:42 min
November 04, 2019

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Summary

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This protocol demonstrates the induction of a hemogenic program in human dermal fibroblasts by enforced expression of the transcription factors GATA2, GFI1B and FOS to generate hematopoietic stem and progenitor cells.

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