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Medicine

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Establishment of a Severe Dry Eye Model Using Complete Dacryoadenectomy in Rabbits
 

Establishment of a Severe Dry Eye Model Using Complete Dacryoadenectomy in Rabbits

Article DOI: 10.3791/60126-v 07:43 min January 8th, 2020
January 8th, 2020

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Summary

A novel approach is presented to induce chronic dry eye disease in rabbits by surgically removing all orbital lacrimal glands. This method, distinct from those previously reported, produces a stable, reproducible model of aqueous deficient dry eye well suited to study tear physiology and pathophysiology and ocular therapeutics.

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Tags

Complete Dacryoadenectomy Severe Dry Eye Model Rabbits Aqueous Deficient Dry Eye Disease Physiology Therapeutic Interventions Lacrimal Glands Tear Production Ocular Surface Tissues Surgical Complications Lidocaine Epinephrine
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