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Journal / Genetics / Måling af mikrobielle Mutations rater med…
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Genetics

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JoVE Journal Genetics
Måling af mikrobielle Mutations rater med udsvings analysen
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Måling af mikrobielle Mutations rater med udsvings analysen

Article DOI: 10.3791/60406-v • 07:44 min • November 28th, 2019
November 28th, 2019 •
1, 2,3, 3, 1, 4, 3
1School of Biological Sciences, The University of Manchester, 2School of Science, University of Waikato, 3School of Natural Sciences, The University of Manchester, 4Department of Mathematics, Université du Québec à Montréal

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Her præsenteres en protokol til at udføre en udsvings analyse og anslå mikrobiel mutation sats ved hjælp af fænotypiske markører. Denne protokol vil gøre det muligt for forskerne at foretage analyse af mutationer i forskellige mikrober og miljøer og bestemme, hvordan genotype og økologisk kontekst påvirker spontane Mutations rater.

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Genetik spontane mutationer mutation rate plasticitet stress-induceret mutagenese Luria-Delbrück fordeling maksimal sandsynlighed estimator celle-celle interaktioner antimikrobiel resistens bakterier
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