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Chronic Post-Ischemia Pain Model for Complex Regional Pain Syndrome Type-I in Rats
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JoVE Journal Behavior
Chronic Post-Ischemia Pain Model for Complex Regional Pain Syndrome Type-I in Rats

Chronic Post-Ischemia Pain Model for Complex Regional Pain Syndrome Type-I in Rats

DOI:
10.3791/60562-v

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07:12 min

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January 21, 2020

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, , , , , , ,
1Department of Neurobiology and Acupuncture Research, The Third Clinical Medical College, Zhejiang Chinese Medical University,Key Laboratory of Acupuncture and Neurology of Zhejiang Province, 2Academy of Chinese Medical Sciences,Zhejiang Chinese Medical University

Chapters

  • 00:04Title
  • 00:43CPIP Model Establishment
  • 02:14Nocifensive Behavioral Tests
  • 04:47Results: Evaluation of the CPIP Rat Model
  • 06:32Conclusion

Summary

Automatic Translation

Automatic Translation

Provided here is a protocol that details steps to establish an animal model of chronic post-ischemia pain (CPIP). This is a well-recognized model mimicking human complex regional pain syndrome type-I. Mechanical and thermal hypersensitivities are further evaluated, as well as capsaicin-induced nocifensive behaviors observed in the CPIP rat model.

Tags

Keywords: CRPS IChronic Post-ischemia PainRat ModelHindlimb EdemaHyperemiaThermal HyperalgesiaMechanical AllodyniaVon Frey FilamentsHargreaves Method

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