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JoVE Journal
Immunology and Infection

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An Immunological Model for Heterotopic Heart and Cardiac Muscle Cell Transplantation in Rats
 

An Immunological Model for Heterotopic Heart and Cardiac Muscle Cell Transplantation in Rats

Article DOI: 10.3791/60956-v 09:25 min
May 8th, 2020

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Summary May 8th, 2020

We describe a model of heterotopic abdominal heart transplantation in rats, implying modifications of current strategies, which lead to a simplified surgical approach. Additionally, we describe a novel rejection model by in-ear injection of vital cardiac muscle cells, allowing further transplant immunological analyses in rats.

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