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JoVE Journal
Immunology and Infection

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Supervised Machine Learning for Semi-Quantification of Extracellular DNA in Glomerulonephritis
 

Supervised Machine Learning for Semi-Quantification of Extracellular DNA in Glomerulonephritis

Article doi: 10.3791/61180
June 18th, 2020

Summary June 18th, 2020

Extracellular DNA (ecDNA) released during cell death is proinflammatory and contributes to inflammation. Measurement of ecDNA at the site of injury can determine the efficacy of therapeutic treatment in the target organ. This protocol describes the use of a machine learning tool to automate measurement of ecDNA in kidney tissue.

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