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Assessment of Stress Effects on Cognitive Flexibility using an Operant Strategy Shifting Paradigm
JoVE Journal
Behavior
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JoVE Journal Behavior
Assessment of Stress Effects on Cognitive Flexibility using an Operant Strategy Shifting Paradigm
DOI:

07:26 min

May 04, 2020

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Chapters

  • 00:04Introduction
  • 00:57Equipment and Software
  • 01:59Stress Procedures
  • 02:35Training
  • 03:40Testing
  • 04:47Results: Behavioral Data and Neuronal Activation from Operant Strategy Shifting Paradigm
  • 06:33Conclusion

Summary

Automatic Translation

Stressful life events impair cognitive function, increasing the risk of psychiatric disorders. This protocol illustrates how stress affects cognitive flexibility using an automated operant strategy shifting paradigm in male and female Sprague Dawley rats. Specific brain areas underlying particular behaviors are discussed, and translational relevance of results are explored.

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