Waiting
Login processing...

Trial ends in Request Full Access Tell Your Colleague About Jove
Journal / Cancer Research / Analyser til validering af Histone…
JoVE Journal
Cancer Research

A subscription to JoVE is required to view this content.

JoVE Journal Cancer Research
Analyser til validering af Histone Acetyltransferase hæmmere
E-Patient Counseling Trial (E-PACO): Computer Based Education versus Nurse Counseling for Patients to Prepare for Colonoscopy
Journal (Cancer Research)
E-Patient Counseling Trial (E-PACO): Computer Based Education versus Nurse Counseling for Patients to Prepare for Colonoscopy
Live-3D-Cell Immunocytochemistry Assays of Pediatric Diffuse Midline Glioma
Journal (Cancer Research)
Live-3D-Cell Immunocytochemistry Assays of Pediatric Diffuse Midline Glioma
 
Click here for the English version

Analyser til validering af Histone Acetyltransferase hæmmere

Article DOI: 10.3791/61289-v • 09:11 min • August 6th, 2020
August 6th, 2020 •
1, 1
1Department of Anatomy and Cell Biology, and UF Health Cancer Center, University of Florida College of Medicine

Chapters

Summary
Automatic Translation

Please note that all translations are automatically generated.

Click here for the English version.

Hæmmere af histone acetyltransferaser (HATs, også kendt som lysin acetyltransferases), såsom CBP/p300, er potentielle terapeutiske til behandling af kræft. Men, strenge metoder til validering af disse hæmmere er nødvendige. Tre in vitro metoder til validering omfatter HAT assays med rekombinant acetyltransferaser, immunoblotting for histone acetylation i cellekultur, og ChIP-qPCR.

Tags

Cancer Research lysin acetyltransferaser KDs CBP/p300 histone acetyltransferase hæmmere screening metoder histone acetylation epigenetik kræft genregulering
Read Article

Get cutting-edge science videos from JoVE sent straight to your inbox every month.

Waiting X
Simple Hit Counter