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Modeling Primary Bone Tumors and Bone Metastasis with Solid Tumor Graft Implantation into Bone
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Chapters
- 00:05Introduction
- 01:18Subcutaneous Tumor Induction
- 03:33Surgical Subcutaneous Tumor Fragment Implantation and Serial and End Point Assessment
- 05:35Results: Representative Serial Radiography
- 06:14Conclusion
Bone metastasis models do not develop metastasis uniformly or with a 100% incidence. Direct intra-osseous tumor cell injection can result in embolization of the lung. We present our technique modeling primary bone tumors and bone metastasis using solid tumor graft implantation into bone, leading to reproducible engraftment and growth.
