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Oxygen-Induced Retinopathy Model for Ischemic Retinal Diseases in Rodents
 

Oxygen-Induced Retinopathy Model for Ischemic Retinal Diseases in Rodents

Article DOI: 10.3791/61482-v
September 16th, 2020

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Summary September 16th, 2020

Oxygen-induced retinopathy (OIR) can be used to model ischemic retinal diseases such as retinopathy of prematurity and proliferative diabetic retinopathy and to serve as a model for proof-of-concept studies in evaluating antiangiogenic drugs for neovascular diseases. OIR induces robust and reproducible neovascularization in the retina that can be quantified.

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