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Oxygen-induceret retinopati Model for iskæmiske retinale sygdomme hos gnavere

Article DOI: 10.3791/61482-v • 09:28 min • September 16th, 2020
September 16th, 2020 •
1,2, 2, 2, 2, 1, 2, 1,3
1Faculty of Medicine and Health Technology, Tampere University & Tampere University Hospital, 2Experimentica Ltd, 3Eye Centre, Tampere University Hospital

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Oxygen-induceret retinopati (OIR) kan bruges til at modellere iskæmiske nethindesygdomme såsom retinopati af prematurity og proliferativ diabetisk retinopati og til at tjene som model for proof-of-concept undersøgelser i evalueringen af antiangiogene lægemidler til neovaskulære sygdomme. OIR fremkalder robust og reproducerbar neovascularisering i nethinden, der kan kvantificeres.

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Medicin angiogenese neovascularization ilt-induceret retinopati OIR hypoxi retinopati af prematurity ROP diabetisk retinopati intravitreal injektion billedanalyse kunstig intelligens AI
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