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In vivo Structural Assessments of Ocular Disease in Rodent Models using Optical Coherence Tomography
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Bioengineering
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JoVE Journal Bioengineering
In vivo Structural Assessments of Ocular Disease in Rodent Models using Optical Coherence Tomography

In vivo Structural Assessments of Ocular Disease in Rodent Models using Optical Coherence Tomography

DOI:
10.3791/61588-v

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07:44 min

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July 24, 2020

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, , ,
1Center of Excellence for Visual and Neurocognitive Rehabilitation,Atlanta Veterans Affairs Medical Center, 2Department of Biomedical Engineering,Georgia Institute of Technology, 3Department of Ophthalmology,Emory University

Chapters

  • 00:04Introduction
  • 00:59Optical Coherence Tomography (OCT) Equipment Setup
  • 02:38Rodent OCT Imaging
  • 03:35Retinal Imaging
  • 04:34OCT Image Post-Processing
  • 05:39Results: Representative In Vivo Ocular Disease Structural Assessment
  • 07:16Conclusion

Summary

Automatic Translation

Automatic Translation

Here, we describe the use of spectral-domain optical coherence tomography (SD-OCT) to visualize retinal and ocular structures in vivo in models of retinal degeneration, glaucoma, diabetic retinopathy, and myopia.

Tags

Optical Coherence TomographySDOCTRetinal DegenerationDiabetic RetinopathyGlaucomaMyopiaRetinal ThicknessAxial LengthRodent ModelsIn VivoRetinal ImagingEye Disease

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