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JoVE Journal
Biochemistry

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A Model Membrane Platform for Reconstituting Mitochondrial Membrane Dynamics
 

A Model Membrane Platform for Reconstituting Mitochondrial Membrane Dynamics

Article DOI: 10.3791/61620-v
September 2nd, 2020

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Summary September 2nd, 2020

Mitochondrial fusion is an important homeostatic reaction underlying mitochondrial dynamics. Described here is an in vitro reconstitution system to study mitochondrial inner-membrane fusion that can resolve membrane tethering, docking, hemifusion, and pore opening. The versatility of this approach in exploring cell membrane systems is discussed.

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