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JoVE Journal
Biology
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Optimization of Crystal Growth for Neutron Macromolecular Crystallography
 

Optimization of Crystal Growth for Neutron Macromolecular Crystallography

Article DOI: 10.3791/61685-v
March 13th, 2021

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Summary March 13th, 2021

Structural studies of biomacromolecules by crystallography require high-quality crystals. Here we demonstrate a protocol that can be used by OptiCrys (a fully automated instrument developed in our lab) and/or microdialysis buttons for growing large high-quality crystals based on knowledge of the crystallization phase diagram.

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