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A Mouse Model of Lumbar Spine Instability

A Mouse Model of Lumbar Spine Instability

Article DOI: 10.3791/61722-v 05:28 min April 23rd, 2021
April 23rd, 2021



We developed a lumbar intervertebral disc degeneration mouse model by resection of L3–L5 spinous processes along with supra- and inter-spinous ligaments and detachment of paraspinous muscles.



Mouse Model Lumbar Spine Instability Surgery Intervertebral Disc Degeneration LSI Mode Special Equipment Reproducible Short Period Of Time Incision Depths Hemorrhage Resection Interspinous Process Experiment Pedal Reflex Anesthetized Mouse Surgical Pad Ointment Small Animal Trimmer Shaved Fur Depilatory Cream Gauze Sterile Saline Surgical Cylindrical Pad Raise Lumbar Spine Expose Vertebrae Subcutaneous Spinous Processes Palpate Lumbar Region Alcohol Rinse Dissecting Microscope
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