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Post-Myocardial Infarction Heart Failure in Closed-chest Coronary Occlusion/Reperfusion Model in Göttingen Minipigs and Landrace Pigs
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Post-Myocardial Infarction Heart Failure in Closed-chest Coronary Occlusion/Reperfusion Model in Göttingen Minipigs and Landrace Pigs

Article DOI: 10.3791/61901-v • 14:35 min • April 17th, 2021
April 17th, 2021 •
*1,2, *1,2, 3,4, 1, 1, 1, 1, 1, 3,4, 3, 3, 5, 5, 5, 5, 6, 6, 7, 1,2
1Department of Pharmacology and Pharmacotherapy, Semmelweis University, 2Pharmahungary Group, 3Diagnostic, Radiation Oncology, Research and Teaching Center, Moritz Kaposi Somogy County Teaching Hospital, 4Faculty of Agricultural and Environmental Sciences, Kaposvar University, 5Heart and Vascular Center, Semmelweis University, 6Quark Pharmaceuticals, Inc, 7Heart Institute, Medical School, University of Pécs
* These authors contributed equally

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Summary
Automatic Translation

The overall goal of the current study is to present the techniques of induction of myocardial infarction (MI) and post-myocardial infarction heart failure (post-MI HF) in closed-chest, adult Göttingen minipigs and the characterization of post-MI HF model in Göttingen minipigs as compared to Landrace pigs.

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Post-myocardial Infarction Heart Failure Closed-chest Coronary Occlusion/reperfusion Model Göttingen Minipigs Landrace Pigs Induction Techniques Myocardial Function Morphology Cardiac Magnetic Resonance Imaging Left Anterior Descending Coronary Artery Balloon Deflation Reperfusion Intercoronary Drug Therapy Thecal Chronic Morpho-functional Consequences Clinical Outcome Cardioprotective Therapies
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