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The Three-Chamber Choice Behavioral Task using Zebrafish as a Model System
JoVE Journal
Behavior
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JoVE Journal Behavior
The Three-Chamber Choice Behavioral Task using Zebrafish as a Model System
DOI:

07:55 min

April 14, 2021

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Chapters

  • 00:05Introduction
  • 00:41Three-Chamber Choice Testing Chamber Preparation and Discrimination Setup
  • 01:39Behavioral Tasks
  • 02:49Acquisition Task
  • 03:25Denoting the Choice Response
  • 04:48Experimental Treatment
  • 05:47Results: Representative Three-Chamber Choice Zebrafish Behavioral Task Analyses
  • 07:21Conclusion

Summary

Automatic Translation

We present a behavioral chamber designed to assess cognitive performance. We provide data showing that once acquired, zebrafish remember the task 8 weeks later. We also show that hyperglycemic zebrafish have altered cognitive performance, indicating that this paradigm is applicable to studies assessing cognition and memory.

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