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Bioengineering

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JoVE Journal Bioengineering
Contrast-Enhanced Subharmonic Aided Pressure Estimation (SHAPE) Using Ultrasound Imaging with a Focus on Identifying Portal Hypertension
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Contrast-Enhanced Subharmonic Aided Pressure Estimation (SHAPE) Using Ultrasound Imaging with a Focus on Identifying Portal Hypertension

Article DOI: 10.3791/62050-v • 06:20 min • December 5th, 2020
December 5th, 2020 •
1, 1,2, 1, 1, 3, 4, 1
1Department of Radiology, Thomas Jefferson University, 2School of Biomedical Engineering, Sciences and Health Systems, Drexel University, 3Department of Medicine, Division of Gastroenterology and Hepatology, Thomas Jefferson University, 4GE Global Research

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Summary
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A protocol for noninvasively estimating ambient pressures utilizing subharmonic ultrasound imaging of infused contrast microbubbles (following appropriate calibration) is described with examples from human patients with chronic liver disease.

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Contrast-enhanced Subharmonic Aided Pressure Estimation SHAPE Ultrasound Imaging Portal Hypertension Non-invasive Measurements Heart Pressure Monitoring Cancer Treatment Monitoring Liver Pressure Measurements Ultrasound Contrast Agent Preparation Syringe Port Chemo Spike Vials Of The Agent Sterile Water Microbubbles Concentration Reconstitution Process Saline Filling Connecting Tubes Three-way Stopcock Extension Tubing Cannula Syringe Pump Ultrasound Scanner C1-6-D Curvilinear Probe Abdominal Preset
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