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Hjerterespons på β-adrenergisk stimulation bestemt af trykvolumen loop analyse
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Hjerterespons på β-adrenergisk stimulation bestemt af trykvolumen loop analyse

Article DOI: 10.3791/62057-v • 08:05 min • May 19th, 2021
May 19th, 2021 •
*1,2, *1,2,3, *1,2,4, 1,2, 1,2
1Pharmakologisches Institut, Ruprecht-Karls-Universität Heidelberg, 2DZHK (German Centre for Cardiovascular Research), partner site Heidelberg/Mannheim, 3Department of Internal Medicine III, University of Heidelberg, 4Department of Anesthesiology, University Hospital RWTH Aachen
* These authors contributed equally

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Her beskriver vi en hjertetryksvolumen loop analyse under stigende doser af intravenøst infunderes isoproterenol at bestemme den iboende hjertefunktion og β-adrenergic reserve i mus. Vi bruger en modificeret åben brysttilgang til trykvolumensløjfemålingerne, hvor vi inkluderer ventilation med positivt endeudløbstryk.

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Medicin Udgave 171 β-adrenergic stimulation isoproterenol hjertefunktion Trykvolumen Loops hjerte mus,in vivo åben bryst
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