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Lumped-Parameter and Finite Element Modeling of Heart Failure with Preserved Ejection Fraction
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JoVE Journal Engineering
Lumped-Parameter and Finite Element Modeling of Heart Failure with Preserved Ejection Fraction

Lumped-Parameter and Finite Element Modeling of Heart Failure with Preserved Ejection Fraction

DOI:
10.3791/62167-v

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09:20 min

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February 13, 2021

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, ,
1Institute for Medical Engineering and Science,Massachusetts Institute of Technology, 2Health Science and Technology Program,Harvard/Massachusetts Institute of Technology, 3Department of Mechanical Engineering,Massachusetts Institute of Technology

Chapters

  • 00:05Introduction
  • 00:43Zero-Dimensional (0D) Lumped-Parameter Model
  • 01:48Finite Element Analysis (FEA) Model
  • 04:38Aortic Valve Stenosis
  • 05:29Heart Failure with Preserved Ejection Fraction (HFpEF) Hemodynamics
  • 06:46Results: Representative Lumped-Parameter and FEA Heart Failure Modeling
  • 08:26Conclusion

Summary

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Automatic Translation

This work introduces two computational models of heart failure with preserved ejection fraction based on a lumped-parameter approach and finite element analysis. These models are used to evaluate the changes in the hemodynamics of the left ventricle and related vasculature induced by pressure overload and diminished ventricular compliance.

Tags

Keywords: Lumped-parameter ModelingFinite Element ModelingHeart FailurePreserved Ejection FractionCardiovascular HemodynamicsComputational ModelingMedical Device DevelopmentHeart ModelingCardiac MechanicsCardiac Electrophysiology

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