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Using a Murine Model of Psychosocial Stress in Pregnancy as a Translationally Relevant Paradigm for Psychiatric Disorders in Mothers and Infants
 

Using a Murine Model of Psychosocial Stress in Pregnancy as a Translationally Relevant Paradigm for Psychiatric Disorders in Mothers and Infants

Article DOI: 10.3791/62464-v 06:39 min June 13th, 2021
June 13th, 2021

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Summary

The chronic psychosocial stress (CGS) paradigm employs clinically relevant stressors during pregnancy in mice to model psychiatric disorders of mothers and infants. Here, we provide a step-by-step procedure of applying the CGS paradigm and downstream assessments to validate this model.

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Tags

Murine Model Psychosocial Stress Pregnancy Psychiatric Disorders Mothers Infants Chronic Stress Psychosocial Insults Animal Model Paradigms Physical Stressors Stressor Regimen Gestational Day Foreign Objects Developmental Origins Of Adult Disease Adverse Intrauterine Events
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