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1Department of Psychiatry and Psychotherapy, Medical Center – University of Freiburg, Faculty of Medicine,University of Freiburg, 2Berta-Ottenstein-Programme for Clinician Scientists, Faculty of Medicine,University of Freiburg, 3Centre National de la Recherche Scientifique (CNRS),Université de Strasbourg, Institut des Neurosciences Cellulaires et Intégratives, 4Department of Stereotactic and Functional Neurosurgery, Medical Center – University Freiburg, Faculty of Medicine,University of Freiburg, 5Center for Basics in Neuromodulation, Faculty of Medicine,University of Freiburg
Chapters
- 00:04Introduction
- 00:57Induction of the Chronic Despair Model
- 02:22Measuring the Immobility Time
- 03:46Results: Evaluation of Anti-Depressive Interventions
- 05:16Conclusion
O modelo de rato de desespero crônico (MDL) da depressão consiste em sessões repetitivas de natação forçada e outra fase de natação retardada como leitura. Representa um modelo adequado para a indução de um estado crônico depressivo estável por pelo menos 4 semanas, para avaliar intervenções de tratamento subcrático e agudo.
