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The Muscle Cuff Regenerative Peripheral Nerve Interface for the Amplification of Intact Peripheral Nerve Signals
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Bioengineering
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JoVE Journal Bioengineering
The Muscle Cuff Regenerative Peripheral Nerve Interface for the Amplification of Intact Peripheral Nerve Signals

The Muscle Cuff Regenerative Peripheral Nerve Interface for the Amplification of Intact Peripheral Nerve Signals

DOI:
10.3791/63222-v

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07:30 min

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January 13, 2022

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, , , , ,
1Department of Surgery, Section of Plastic Surgery,The University of Michigan Health System, 2Department of Biomedical Engineering,The University of Michigan, Ann Arbor

Chapters

  • 00:05Introduction
  • 01:04Preparation of the Muscle Graft
  • 02:37Common Peroneal Nerve Isolation and Preparation
  • 03:56MC-RPNI Construct Fabrication
  • 04:57Results: Histological and Electrophysiological Analysis of the MC-RPNI Fabrication
  • 06:26Conclusion

Summary

Automatic Translation

Automatic Translation

This manuscript provides an innovative method for developing a biologic peripheral nerve interface termed the Muscle Cuff Regenerative Peripheral Nerve Interface (MC-RPNI). This surgical construct can amplify its associated peripheral nerve's motor efferent signals to facilitate accurate detection of motor intent and the potential control of exoskeleton devices.

Tags

Keywords: Muscle Cuff Regenerative Peripheral Nerve InterfaceMC-RPNIPhysiologic Nerve SignalsMicrovoltsMotor IntentPowered Exoskeleton DevicesBiological Nerve Signal AmplificationEDL MuscleTenotomyNerve GraftEndomysium

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