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Somministrazione efficace di interferenza orale dell'RNA (RNAi) alle zanzare Anopheles gambiae adulte
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Somministrazione efficace di interferenza orale dell'RNA (RNAi) alle zanzare Anopheles gambiae adulte

Article DOI: 10.3791/63266-v • 07:48 min • March 1st, 2022
March 1st, 2022 •
1,2, 1, 3, 4,5, 5,6, 1, 5,7,8
1Division of Parasitic Diseases and Malaria, Entomology Branch, Centers for Disease Control and Prevention, 2Department of Entomology, Cornell University, 3Centro de Estudios en Biotecnologia, Universidad del Valle de Guatemala, 4Department of Cell Biology, Johns Hopkins School of Medicine, 5Johns Hopkins Malaria Research Institute, Johns Hopkins Bloomberg School of Public Health, 6Department of Molecular Microbiology and Immunology, Johns Hopkins Bloomberg School of Public Health and Malaria Research Institute, 7Department of Cell Biology, Johns Hopkins School of Medicine, 8Biomedical Sciences Department, Idaho College of Osteopathic Medicine

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La somministrazione orale di dsRNA prodotto dai batteri, un metodo di consegna per l'interferenza dell'RNA (RNAi) che viene regolarmente utilizzato in Caenorhabditis elegans, è stato applicato con successo qui alle zanzare adulte. Il nostro metodo consente robusti studi di genetica inversa e studi vettoriali che bloccano la trasmissione senza l'uso dell'iniezione.

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Biologia Numero 181
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