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Bioinformatics Resources for the Study of Glycan-Mediated Protein Interactions

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Biology

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Bioinformatics Resources for the Study of Glycan-Mediated Protein Interactions

Bioinformatics Resources for the Study of Glycan-Mediated Protein Interactions

DOI:

10.3791/63356-v

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11:21 min

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January 20, 2022

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Frédérique Lisacek^2,3

¹Proteome Informatics Group,SIB Swiss Institute of Bioinformatics, ²Computer Science Department,University of Geneva, ³Section of Biology,University of Geneva

Chapters

00:05Introduction
01:11Accessing Resources from Glyco@Expasy and Exploring the Contextual Information of a Protein N-Glycome
02:43Visualizing and Correlating the Contextual Information of a Protein N-Glycome
05:38Glycan-Binding Information in UniLectin
06:59Browsing the HGI Challenge High Confidence Dataset
07:45Comparing the O-Glycome of a Selected Serum Protein in GlyConnect
08:47Results: Combining Outputs of GlyConnect Octopus, GlyConnect Compozitor, and UniLectin
10:49Conclusion

Summary

Automatic Translation

This protocol illustrates how to explore, compare, and interpret human protein glycomes with online resources.

Tags

Keywords: Bioinformatics Glycoinformatics Glycomics Glycoproteomics Glycan-mediated Protein Interactions Glycoproteome GlyConnect Prostate-specific Antigen (PSA)Glycan Structures Glycan Compositions Octopus N-linked Glycans Hybrid Glycans Sialylated Glycans

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