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Flexible Organic Electronic Devices for Pulsed Electric Field Therapy of Glioblastoma
JoVE Journal
Cancer Research
This content is Free Access.
JoVE Journal Cancer Research
Flexible Organic Electronic Devices for Pulsed Electric Field Therapy of Glioblastoma
DOI:

11:02 min

August 09, 2022

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Chapters

  • 00:05Introduction
  • 00:57Flexible Device Microfabrication
  • 03:573D Models for Spheroid Culture
  • 05:063D Models for the In Ovo Culture
  • 06:02Implantation of Flexible Interdigitated Electrodes for the In Vivo Model
  • 08:24Results: Characterization of Flexible Interdigitated Electrodes and Implementation in Brain Tumor Models
  • 10:11Conclusion

Summary

Automatic Translation

This work describes the development of flexible interdigitated electrodes for implementation in 3D brain tumor models, namely, in vitro culture, in ovo model, and in vivo murine model. The proposed method can be used to evaluate the effects of pulsed electric fields on tumors at different levels of complexity.

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