Presented here is a description of the straightforward and relatively rapid isolation of Caenorhabditis elegans genomic DNA from one or a few animals using a commercially available tissue kit. The resulting gDNA preparation is a suitable template for PCR.
Madhu, B., Lakdawala, M. F., Gumienny, T. L. Small-Scale Extraction of Caenorhabditis elegans Genomic DNA. J. Vis. Exp. (184), e63716, doi:10.3791/63716 (2022).