Fragmenting Bulk Hydrogels and Processing into Granular Hydrogels for Biomedical Applications

Granular hydrogels are an exciting new class of biomaterials with many advantageous properties. Our hope is that in sharing these methods, we can increase the access and innovation in granular hydrogels for biomedical applications. This technique is simple, low-cost, easily adaptable to many chemistries and can be implemented in virtually any laboratory.

Load a 3-milliliter syringe with the hydrogel precursor solution. Remove the plunger from the back of an empty 3-milliliter syringe and add a tip cap to the top of the syringe barrel. Use a 1, 000-microliters pipette to transfer the hydrogel precursor solution into the syringe barrel with the tip cap.