Here, we present an experimental imaging protocol for the quantification of cardiac function and morphology using high-resolution positron emission tomography/computed tomography for small animals. Both mice and rats are considered, discussing the different requirements of computed tomography contrast agents for the two species.
Panetta, D., Guzzardi, M. A., La Rosa, F., Granziera, F., Terlizzi, D., Kusmic, C., Iozzo, P. High-Resolution Cardiac Positron Emission Tomography/Computed Tomography for Small Animals. J. Vis. Exp. (190), e64066, doi:10.3791/64066 (2022).