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Выделение и прямое нейрональное перепрограммирование астроцитов мыши
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Выделение и прямое нейрональное перепрограммирование астроцитов мыши

Article DOI: 10.3791/64175-v • 07:25 min • July 7th, 2022
July 7th, 2022 •
1,2,3, 2, 1,2
1Institute of Stem Cell Research, Helmholtz Zentrum München, German Research Center for Environmental Health, 2Department of Physiological Genomics, Biomedical Center Munich, Ludwig-Maximilians University, 3Graduate School of Systemic Neurosciences, BioCenter, Ludwig-Maximilians University

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Здесь описан подробный протокол генерации высокообогащенных культур астроцитов, полученных из разных областей центральной нервной системы постнатальных мышей и их прямого преобразования в функциональные нейроны путем принудительной экспрессии факторов транскрипции.

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Неврология Выпуск 185
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